All countries need data, information and knowledge to identify threats to biodiversity, and determine needs and priorities, plan and take evidence-based decisions and actions, set benchmarks and monitor and report on progress for the conservation and sustainable use of biodiversity and the fair and equitable benefits arising from the utilization of genetic resources. Accessible biodiversity-related data, information and knowledge are critical for creating baselines, regularly assessing progress and taking necessary action. This issue is cross-cutting, with implications for all the goals and targets of the Kunming-Montreal Global Biodiversity Framework.